Jun 26, 2010 antidiabetic effect of the alcoholic extract of otostegia persica was investigated on 40 streptozotocin diabetic rats in four equal groups. Moreover, the greatly modified fixed ratios method in this study can be considered as a useful method for. Glucosidases are a group of enzymes playing crucial roles in digestion of carbohydrates. An efficient onepot synthesis of 1,4disubstituted 1,2,3. Three plants namely, otostegia persica, salvia mirzayanii and zataria multiflora are used as antidiabetic agents in the traditional medicine of hormozgan and fars provinces, iran. The effects of contact time 0120 min, the initial ph 38, biomass dosage 0. Although the leaves of otostegia integrifolia traditionally claimed in ethiopian folklore medicine for management of diabetes mellitus, it has not been validated. Forty eight male wistar rats were randomized into three study groups of 16 rats each. Several industries have undergone a facelift to have a smooth sailing since internet is ruling every market. Methanolic leaf exctract of otostegia integrifolia benth. Labiatae comprises 20 species, no previous antimicrobial investigation of this genus has been reported, and however there are reports on the anti insect activity of o. To measure the enzyme inhibition, 5 and 20 mgml of the extracts, and to measure. The ethyl acetate fraction of otostegia persica 99. Cultivation, genetic, ethnopharmacology, phytochemistry.
The labiatae is one of the largest plant families grown globally and many studies that have isolated new pharmaceutical compounds. In this study, the hepatoprotective effect of the methanol extract of aerial parts shoot from otostegia persica boiss golder was investigated against the carbon tetrachloride ccl4induced acute hepatotoxicity in male rats. This article is from avicenna journal of phytomedicine, volume 4. The board of trustees of the royal botanic gardens, kew. Forty male wistar rats were randomly divided into five equal groups and treated as follows. The two extracts also showed good antioxidant activity as well. Diabetes affects 12% of the population and there are around 100 million worldwide. Pdf otostegia persica extraction on healing process of. The aim of this study was therefore to investigate the antidiabetic activity of otostegia integrifolia in rodents. Downloaded by yale university library on 09052017 21. In this study, comparative evaluation of the effect of hydroalcoholic extract and quercetin of otostegia persica boiss with atorvastatin on abc.
Effect of otostegia persica extraction on renal injury induced by hindlimb. Antiglycation, otostegia persica, 3,7dihydroxy4,6,8trimethoxyflavone. Otostegia persica boiss lamiaceae significantly decreased glycemia in diabetic rats 14 h after treatment, parallel to an increase in the serum insulin level. Pdf otostegia persica extraction on healing process of burn. This extract also significantly decreased mda and increased gsh levels in the liver of diabetic rats. Chemical composition, antimicrobial, and cytotoxic activities. Otostegia persica has been explored exhaustively for its phytochemical, pharmacological, and ethnopharmacological activities. Determination of antioxidant and antimicrobial activities. Otostegia in world checklist of selected plant families. Antidiabetic effect of orally administered otostegia persica. In folk medicine, some of labiatae plants such as zataria multiflora boiss, salvia mirzayanii rech.
No warranties or guarantees as to the accuracy of the data and information derived from this web site are expressed or implied. Choose format ris procit, reference manager bibtex refworks direct export. Pdf phytochemical and antidiabetic investigations of. In an attempt to identify herbal drugs which may become useful in the prevention of diabetes, antioxidant potentials and. Otostegia persica is called golder locally yassa et al. References this hymenopodidaerelated article is a stub. May 18, 2018 the extracts from the leaves of otostegia integrifolia have been reported to show phytochemical analysis, total flavonoid content, antioxidant and antibacterial activities.
The current study summarizes the updated information concerning the. The role of metals in mammalian olfaction of low molecular weight. Liver damage was induced through the oral administration of 50% ccl4 in liquid paraffin 2. Effect of otostegia persica extraction on renal injury induced by hindlimb ischemiareperfusion. Regarding the antioxidant property of otostegia persica extract and the role of antioxidants in diabetes mellitus treatment, in this study the e. Phytochemical and antidiabetic investigations of otostegia persica from iran. Comparative investigation of the effect of quercetin and. Determination of antioxidant and antimicrobial activities of. Animals in the first group did not receive any extract and acted as a control for the other groups. Chemical composition, antimicrobial, and cytotoxic. Since the antioxidant activity of different extracts and fractions of aerial parts of otostegia persica has been evaluated and this plant is used as an antidiabetic agent in iranian traditional medicine, we evaluated the antiglycation activity of this species.
Antidiabetic effects of otostegia persica root in alloxan. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs alternatively, you can download the pdf file directly to your computer, from where it. Thus, in this study the effect of aqueous extract of o. An efficient onepot synthesis of 1,4disubstituted 1,2,3triazoles at room temperature by green synthesized cu nps using otostegia persica leaf extract mahmoud nasrollahzadeh, s.
Iran 2biotechnology research center and school of pharmacy, mashhad university of medical sciences, mashhad, i. Otostegia persica as a source of natural antioxidants pharmaceutical. Phytochemical investigation and microscopic analysis of aerial parts of otostegia persica. Pdf antiglycation activity of otostegia persica burm. Stereological study of the effects of orally administrated. Pdf phytochemical investigation and microscopic analysis. The otostegia persica is traditionally used in some regions of iran as medicinal herb for antidiabetic properties. Green synthesis of cu nps using aqueous extract of the otostegia persica leaves.
Otostegia persica potentiated the effectiveness of chloroquine against the chloroquinesensitive strain of p. Antidiabetic effect of the alcoholic extract of otostegia persica was investigated on 40 streptozotocin diabetic rats in four equal groups. Seyed abdul majid ayatollahi 1,2, farzad kobarfard 1,3, jinous asgarpanah 4 and muhammad. Pretreatment of otostegia persica extraction decreased this ratio compared with no otostegia persica extraction in the ischemiareperfusion group p download. Scientific note toxic and repellent effect of harmal peganum. Renal functional and biochemical markers were estimated. Our results revealed that the total flavonoid content of methanol and ethyl acetate extracts is 416. This study investigates the inhibitory effects of different fractions of three mentioned species extracts on. Biosorption characteristics of pbii ions from aqueous solution were studied using some residues of solventextracted otostegia persica known as goldar residue biomass. If you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs. Burn wounds were created on dorsal part of shaved rats using a metal rod.
Otostegia persica extract was used as a traditional medicine for the management of diabetes mellitus in humans in some parts of iran. Otostegia persica extraction on healing process of burn. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader. Persica definition of persica by the free dictionary. Batsch, belonging to the family rosaceae and prunus genus, reaching the 14th position in the ranking of world peach production faostat, 2015, where the southern states stand out for presenting climatologic conditions which support its commercial exploration embrapa, 2005 and the state of rio. Glucosidase inhibitors can reduce carbohydrate digestion rate and have the potential to prevent development of type 2 diabetes. Antioxidant activity of otostegia persica labiatae and its constituents. Methanolic extract of otostegia persica has been exhibited strong antioxidant activity 7. The california polytechnic state university and the cal poly corporation shall not be responsible for any loss of profit, indirect, incidental, special, or consequential damages arising out of the use of the data and information derived from this web site. The two extracts also showed good antioxidant activity as. Pdf antidiabetic effect of otostegia persica extract on.
Male rats or mice were randomly divided into five groups for diabetic, hypoglycemic and glucose tolerance test ogtt. Acetonic extract on several aphids and tribolium castaneum herbst elham salari1, 2, kamal ahmadi 1, reza zamani dehyaghobi1, 2, amin purhematy 1, and haji mohammad takalloozadeh1. Hepatoprotective effect of otostegia persica boiss. By seyed abdul, majid ayatollahi, farzad kobarfard, jinous asgarpanah and iqbal choudhary. Zahedan journal of research in medical sciences the effect. Effect of otostegia persica extraction on renal injury. Since the antioxidant activity of different extracts and fractions of aerial parts of otostegia persica has been evaluated and this plant is used as an antidiabetic agent in iranian traditional medicine, we evaluated the antiglycation activity of this. Publish projects, dissertation, theses, books, souvenir, conference proceeding with isbn. On the 15th day, ischemia was induced in left kidney for 60 min, followed by reperfusion for 24h. Scientific note toxic and repellent effect of harmal peganum harmala l. The structures of the compounds 14 were established by their spectral data and their relative configuration was determined by 2d nmr. The extracts from the leaves of otostegia integrifolia have been reported to show phytochemical analysis, total flavonoid content, antioxidant and antibacterial activities.
In the present study oral administration of the aqueous extract of otostegia persica root 200, 300 and 400 mgkg body wt. This article aims to provide an overview of the chemical constituents present in o. Ethnopharmacology, phytochemistry and pharmacology of. Acetonic extract on several aphids and tribolium castaneum herbst. Antidiabetic effect of orally administered otostegia.
The leaf essential oil of otostegia fruticosa subsp. Rats in group ii, iii, and iv received a daily oral dose of o. An efficient onepot synthesis of 1,4disubstituted 1,2,3triazoles at room temperature by green synthesized cu nps using otostegia persica leaf extract. Effect of otostegia persica extract on ischemiareperfusion. Introduction diabetes mellitus is an endocrine disorder characterized by chronic hyperglycemia which results for a deficiency of or resistance to insulin. The effect of otostegia persica in combination with.
Effect of otostegia persica op on urinary excretion rate. The level of serum glucose, total cholesterol, triglyceride tg, high density ipoprotein cholesterol hdlc, low density lipoprotein cholesterol ldlc, aspartate amino transferase ast. Oxyothespis persica is a species of praying mantis in the genus oxyothespis in the order mantodea. Hypercholesterolemia is an independent risk factor for atherosclerosis that the use of medicinal plants with minimal side effects is very important in the treatment of it. Thirtytwo matured normoglycemic male spraguedawley rats, weighing 180220 g, were selected and. In brazil, the main species of stone fruit cultivated is the peach tree prunus persica l. The present study was conducted to investigate the effect of ethanolic extract of otostegia persica on bone loss in streptozotocin stztreated diabetic rats. Welcome to persica torontos best currency exchange service provider there has been a sea of change in the world with the advancement in technology, particularly because of the internet.
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